Perioperative Care of a Patient With Carney Complex

Abstract

Carney complex is a multiple endocrine neoplasia syndrome, commonly affecting the thyroid, adrenal, and pituitary glands. In addition to endocrine involvement, tumors and myxomas may develop including cardiac myxomas and schwannomas. Approximately 70% of cases result from autosomal dominant germline mutation, with the remaining 30% representing de novo spontaneous mutations. Carney complex remains extremely rare, with only approximately 750 cases reported worldwide since 1985. We present an adolescent with Carney complex who underwent left atrial myxoma resection, followed by bilateral adrenalectomy a few years later. The perioperative implications of Carney complex are presented, previous reports of anesthetic care in these patients reviewed, and options for anesthetic management discussed.